Title:
しわ、細かいすじ及び発汗過多の治療のための組成物及び伝達方法
Document Type and Number:
Japanese Patent JP2006514657
Kind Code:
A
Abstract:
The present invention describes compositions and methods for treating, preventing and improving the appearance of skin, particularly, treating, preventing, ameliorating, reducing and/or eliminating fine lines and/or wrinkles of skin, wherein the compositions include limonoid constituents which inhibit acetylcholine release at neuromuscular junctions of skeletal muscle so as to relax the muscles involved with wrinkling, folding and creasing of skin, e.g., facial movement and expression. The limonoids preferably include the plant alkaloids toosendanin and azadirachtin. The compositions, which also are used to treat hyperhidrosis, are preferably applied to the skin, or are delivered by directed means to a site in need thereof.
Inventors:
Lou, Mitchell Tsuen
Karavsky, Robert E
Dougan, Mitchell Sea
Karavsky, Robert E
Dougan, Mitchell Sea
Application Number:
JP2004565599A
Publication Date:
May 11, 2006
Filing Date:
December 17, 2003
Export Citation:
Assignee:
Avon Products Incorporated
International Classes:
A61K8/00; A61K8/02; A61K8/04; A61K8/14; A61K8/96; A61K8/97; A61K31/00; A61K31/01; A61K31/045; A61K31/365; A61K36/00; A61K36/18; A61K36/752; A61K45/06; A61P17/16; A61P43/00; A61Q15/00; A61Q17/04; A61Q19/00; A61Q19/08; A61Q19/10
Domestic Patent References:
| JPH07138180A | 1995-05-30 | |||
| JP2001316239A | 2001-11-13 | |||
| JP2002284676A | 2002-10-03 | |||
| JP2000511900A | 2000-09-12 | |||
| JPH08508717A | 1996-09-17 |
Foreign References:
| WO2001012206A2 | 2001-02-22 |
Attorney, Agent or Firm:
Takehiko Saito
Yasuyuki Hata
Yasuyuki Hata