Title:
ホスファターゼのインヒビター
Document Type and Number:
Japanese Patent JP2006514658
Kind Code:
A
Abstract:
The present invention relates to compounds that inhibit phosphatases, compositions thereof, and methods of using those compounds and compositions for treating diseases.
Inventors:
Sanders, Jeffrey Oh.
Mikuniz, Gregory F.
Buck Melter, Alexandre Jay.
Hunt, Kevin W.
Blake, James F.
Biggers, Guy P. A.
Sun, shichen
Mikuniz, Gregory F.
Buck Melter, Alexandre Jay.
Hunt, Kevin W.
Blake, James F.
Biggers, Guy P. A.
Sun, shichen
Application Number:
JP2004565845A
Publication Date:
May 11, 2006
Filing Date:
December 31, 2003
Export Citation:
Assignee:
VERTEX PHARMACEUTICALS INCORPORATED
International Classes:
C07D209/16; A61K9/00; A61K9/24; A61K9/28; A61K31/4045; A61K31/517; A61K31/58; A61K31/635; A61K31/7072; A61K45/06; A61L31/00; A61P1/04; A61P1/16; A61P3/10; A61P7/00; A61P7/06; A61P13/12; A61P17/02; A61P17/06; A61P19/02; A61P21/04; A61P25/00; A61P27/02; A61P35/00; A61P35/02; A61P37/02; A61P37/06; A61P37/08; A61P43/00; C07D401/12; C07D405/06; C07D405/14
Domestic Patent References:
| JPH09506102A | 1997-06-17 | |||
| JPH03181469A | 1991-08-07 |
Foreign References:
| WO2002064572A1 | 2002-08-22 | |||
| WO1998018781A2 | 1998-05-07 | |||
| WO2001004103A1 | 2001-01-18 | |||
| WO2002020525A2 | 2002-03-14 | |||
| WO1998027092A1 | 1998-06-25 |
Other References:
JPN6010024723, ＧＯＲＤＥＥＶ，Ｍ．Ｆ． ｅｔ ａｌ．, "Ａ ｇｅｎｅｒａｌ ａｎｄ ｅｆｆｉｃｉｅｎｔ ｓｏｌｉｄ ｐｈａｓｅ ｓｙｎｔｈｅｓｉｓ ｏｆ ｑｕｉｎａｚｏｌｉｎｅ−２，４−ｄｉｏｎｅｓ", Ｔｅｔｒａｈｅｄｒｏｎ Ｌｅｔｔｅｒｓ, 1997, Ｖｏｌ．３８， Ｎｏ．１０, ｐ．１７２９−１７３２
JPN6010024725, ＭＡＬＡＭＡＳ，Ｍ．Ｓ． ｅｔ ａｌ．, "Ｑｕｉｎａｚｏｌｉｎｅａｃｅｔｉｃ ａｃｉｄｓ ａｎｄ ｒｅｌａｔｅｄ ａｎａｌｏｇｓ ａｓ ａｌｄｏｓｅ ｒｅｄｕｃｔａｓｅ ｉｎｈｉｂｉｔｏｒｓ", Ｊｏｕｒｎａｌ ｏｆ Ｍｅｄｉｃｉｎａｌ Ｃｈｅｍｉｓｔｒｙ, 1991, Ｖｏｌ．３４， Ｎｏ．４, ｐ．１４９２−１５０３
JPN6010024725, ＭＡＬＡＭＡＳ，Ｍ．Ｓ． ｅｔ ａｌ．, "Ｑｕｉｎａｚｏｌｉｎｅａｃｅｔｉｃ ａｃｉｄｓ ａｎｄ ｒｅｌａｔｅｄ ａｎａｌｏｇｓ ａｓ ａｌｄｏｓｅ ｒｅｄｕｃｔａｓｅ ｉｎｈｉｂｉｔｏｒｓ", Ｊｏｕｒｎａｌ ｏｆ Ｍｅｄｉｃｉｎａｌ Ｃｈｅｍｉｓｔｒｙ, 1991, Ｖｏｌ．３４， Ｎｏ．４, ｐ．１４９２−１５０３
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita