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Title:
タキキニン拮抗薬としてのテトラヒドロピラン化合物
Document Type and Number:
Japanese Patent JP2006519822
Kind Code:
A
Abstract:
The present invention relates to compounds of formula (Ia) wherein A, B, n, m, R1, R2, R3, R4, R5, R6, R7, R8, R9, R10 and R11 are defined herein, and pharmaceutically acceptable salts thereof; the compounds are of particular use in the treatment or prevention of depression, anxiety, pain, inflammation, migraine, emesis or postherpetic neuralgia.

Inventors:
Deira, Olivier
Elliott, The Eason Machine
Huscroft, Ian Thomas
Jerry, Richard Yard Alexander
Kragowski, Janusyu Youssef
Lavo, Pyotr Antoni
Duncan Edward, Chiyo
Sternfield, Francine
Swain, Christopher Jiyoung
Application Number:
JP2006505915A
Publication Date:
August 31, 2006
Filing Date:
March 04, 2004
Export Citation:
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Assignee:
Merck Sharp End Dome Limited
International Classes:
C07D309/10; A61K31/351; A61K31/397; A61K31/4025; A61K31/424; A61K31/438; A61K31/453; A61K31/541; A61P1/08; A61P25/00; A61P25/04; A61P25/06; A61P25/22; A61P25/24; A61P29/00; A61P43/00; C07D405/04; C07D405/06; C07D407/04; C07D407/12; C07D417/04; C07D491/10; C07D491/107; C07D498/04
Attorney, Agent or Firm:
Yoshio Kawaguchi
Makoto Ono
Kenkyo Kanayama
Katsuma Osaki
Mitsuaki Tsubokura