Title:
徐放性が向上した経口用医薬送達システム
Document Type and Number:
Japanese Patent JP2006525342
Kind Code:
A
Abstract:
A solid oral delivery system having improved sustained release properties made of at least one lipid, dry particles including at least one pharmaceutical, and at least one filler, wherein the dry particles are continuously coated by the lipid and form a homogeneous suspension with the lipid, wherein the suspension, when melted, exhibits thixotropic and/or pseudoplastic properties, wherein the suspension is formed into the desired dose by molding or pouring the suspension when in a liquid or semi-liquid state. The process for preparing the present delivery system by melting the lipid, blending the dry particles which include the pharmaceutical, at least one filler and, optionally, flavorings with the melted lipid, and pouring or molding the suspension to provide the solid dose, wherein the suspension, when melted, exhibits thixotropic and pseudoplastic flow properties.
Inventors:
Kirshman Alvin
Shah Jeff El
Shah Jeff El
Application Number:
JP2006513410A
Publication Date:
November 09, 2006
Filing Date:
April 28, 2004
Export Citation:
Assignee:
Shah/Kirshman Laboratories, Inc.
International Classes:
A61K9/50; A61K9/20; A61K9/22; A61K9/52; A61K47/36
Foreign References:
| WO2001049272A2 | 2001-07-12 | |||
| US4749575A | 1988-06-07 |
Attorney, Agent or Firm:
Sadao Kumakura
Nobuo Ogawa
Atsushi Hakoda
Kenji Asai
Koji Hirayama
Nobuo Ogawa
Atsushi Hakoda
Kenji Asai
Koji Hirayama