Title:
小分子免疫増強因子およびその検出のためのアッセイ
Document Type and Number:
Japanese Patent JP2008504286
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide new immune potentiators, immunogenic compositions, new compounds and pharmaceutical compositions, and new methods for administering a vaccine, by administering small molecule immune potentiators in combination with antigens.SOLUTION: The invention provides immunostimulatory compositions comprising a small molecule immuno-potentiator (SMIP) compound and methods of administration thereof. Also methods for administering an SMIP compound in an effective amount to enhance the immune response of a subject to an antigen are provided. Further new compositions and methods for administering SMIP compounds alone or in combination with another agent for the treatment of cancer, infectious diseases and/or allergies/asthma are provided. In a further aspect, the invention relates generally to methods for screening of small molecule immuno-modulatory compositions.
Inventors:
Variante, Nicholas
Shoe, fen
Shoe, fen
Application Number:
JP2007518321A
Publication Date:
February 14, 2008
Filing Date:
June 24, 2005
Export Citation:
Assignee:
Chiron Corporation
International Classes:
A61K31/7056; A61K31/16; A61K31/336; A61K31/353; A61K31/366; A61K31/4439; A61K31/4706; A61K31/50; A61K31/575; A61K38/00; A61K39/39; A61K45/00; A61P11/06; A61P31/12; A61P31/14; A61P35/00; A61P37/02; A61P37/08; G01N33/53; G01N37/00; C07K7/66
Domestic Patent References:
| JP2004155777A | 2004-06-03 | |||
| JP2008504292A | 2008-02-14 |
Foreign References:
| US4017608A | 1977-04-12 | |||
| US20050037018A1 | 2005-02-17 |
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita