Title:
置換キラル縮合[1,2]イミダゾ[4,5-c]環状化合物
Document Type and Number:
Japanese Patent JP2008529974
Kind Code:
A
Abstract:
Substituted fused [1,2]imidazo[4,5-c] ring compounds (e.g., imidazo[4,5-c]quinolines, 6,7,8,9-tetrahydroimidazo[4,5-c]quinolines, imidazo[4,5-c]naphthyridines, and 6,7,8,9-tetrahydroimidazo[4,5-c]naphthyridines) with a —CH(—R1)— group in the fused ring at the 1-position of the imidazo ring, wherein R1 includes a functional group, for example, an amide, sulfonamide, urea, carbamate, ester, ketone, ether, a thio analog of the forgoing, sulfone, oxime, or hydroxylamine, pharmaceutical compositions containing the compounds, intermediates, methods of making the compounds, and methods of use of these compounds as immunomodulators, for inducing cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases, are disclosed.
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Inventors:
Grease Glover, George W.
Kushir Sagar, Tusha A.
Slania, Sara Jay.
Danielson, Michael Yee.
Kushir Sagar, Tusha A.
Slania, Sara Jay.
Danielson, Michael Yee.
Application Number:
JP2007549597A
Publication Date:
August 07, 2008
Filing Date:
December 29, 2005
Export Citation:
Assignee:
3M INNOVATIVE PROPERTIES COMPANY
International Classes:
C07D471/14; A61K31/4985; A61K31/5377; A61K31/5383; A61P17/00; A61P27/16; A61P31/12; A61P31/14; A61P35/00; A61P37/08; C07D498/14
Domestic Patent References:
| JP2008526754A | 2008-07-24 |
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Ryotaro Takei
Takashi Ishida
Fukumoto product
Tetsuji Koga
Ryotaro Takei