Title:
2-アミノ-4-フェニルキナゾリン誘導体およびHSP90モジュレーターとしてのその使用
Document Type and Number:
Japanese Patent JP2008540587
Kind Code:
A
Abstract:
Novel phenylquinazoline derivatives of the formula (I), in which R1, R2, R3, R4 and R5 have the meanings indicated in Claim 1, are HSP90 inhibitors and can be used for the preparation of a medicament for the treatment of diseases in which the inhibition, regulation and/or modulation of HSP90 plays a role.
Inventors:
Egen Weiler, Hans-Michael
Wolf, michael
Buchstaller, Hans-Peter
Wolf, michael
Buchstaller, Hans-Peter
Application Number:
JP2008511580A
Publication Date:
November 20, 2008
Filing Date:
April 24, 2006
Export Citation:
Assignee:
Merck Patent Gesellschaft mit beschraenkter Haftung
International Classes:
C07D239/84; A61K31/517; A61P1/04; A61P1/16; A61P3/10; A61P9/00; A61P9/10; A61P11/00; A61P11/06; A61P13/12; A61P15/00; A61P17/02; A61P17/06; A61P19/02; A61P21/00; A61P25/00; A61P25/14; A61P25/28; A61P27/02; A61P29/00; A61P31/00; A61P31/12; A61P31/18; A61P31/20; A61P31/22; A61P35/00; A61P35/02; A61P35/04; A61P37/06; A61P39/00; A61P43/00; C07D403/12
Domestic Patent References:
| JPH06192099A | 1994-07-12 |
Foreign References:
| WO2005021552A1 | 2005-03-10 |
Attorney, Agent or Firm:
Akio Miyazaki
Ishibashi Masayuki
Masaaki Ogata
Ishibashi Masayuki
Masaaki Ogata