invivoでのタンパク質の連続的な目的に適合した進化のための方法

Title:

invivoでのタンパク質の連続的な目的に適合した進化のための方法

Document Type and Number:

Japanese Patent JP2009504144

Kind Code:

A

Abstract:

The present invention relates to methods for producing variants of proteins which have improved properties in comparison with the initial protein, the variants being obtained with the aid of an in vivo evolution method.

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Inventors:

Michael squirrel

Application Number:

JP2008525457A

Publication Date:

February 05, 2009

Filing Date:

August 07, 2006

Export Citation:

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Assignee:

GENEART AG

International Classes:

C12P21/02; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/09

Domestic Patent References:

JP2002515224A	2002-05-28
JP2002515224A	2002-05-28

Foreign References:

WO2004039995A1	2004-05-13
WO2004039995A1	2004-05-13

Other References:

JPN6011036229; ＦＡＳＥＢ　Ｊ．７（１０）, 1993, ９５７-６３
JPN6011036232; Ｐｒｏｃ．　Ｎａｔｌ．　Ａｃａｄ．　Ｓｃｉ．　ＵＳＡ１０２（１６）, 20050419, ５６９１-６

Attorney, Agent or Firm:

Toshio Yano
Toshiomi Yamazaki
Takuya Kuno
Hiroshi Sugimoto
Kimihiro Hoshi
Hiroyasu Ninomiya
Einzel Felix-Reinhard
Reinhard Einsel

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