Title:
snRNA遺伝子様転写単位及びその使用
Document Type and Number:
Japanese Patent JP2009508483
Kind Code:
A
Abstract:
By a computer search for upstream promoter elements (DSE, PSE) typical of small nuclear RNA (snRNA) genes, we have identified a number of previously unrecognized, putative transcription units whose predicted products are novel noncoding RNAs with homology to protein-coding genes. By elucidating the function of one of them, we provide evidence for the existence of a sense/antisense-based gene regulation network where part of the Pol III transcriptome could control its Pol II counterpart.
Inventors:
Aldo Pagano
Application Number:
JP2008530759A
Publication Date:
March 05, 2009
Filing Date:
September 19, 2006
Export Citation:
Assignee:
Universita Degli Study di Genova
International Classes:
C12N15/09; C12M1/00; C12N15/11; C12Q1/68; G01N37/00
Other References:
JPN6012016554; Ｂｉｏｃｈｅｍ． Ｂｉｏｐｈｙｓ． Ｒｅｓ． Ｃｏｍｍｕｎ．， ２７４［３］（２０００） ｐ．６４１-６４８
JPN5008014387; ＺＥＮＴＩＬＩＮ Ｌ．: ＣＵＲＲＥＮＴ ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ ＢＩＯＴＥＣＨＮＯＬＯＧＹ Ｖ５ Ｎ４, 200408, Ｐ３４１-３４７, ＢＥＮＴＨＡＭ ＳＣＩＥＮＣＥ ＰＵＢＬＩＳＨＥＲＳ
JPN6012016555; Ｏｒａｌ Ｏｎｃｏｌ．， ４１［７］（２００５-０８） ｐ．７１６-７２２
JPN6012016552; Ｎｕｃｌｅｉｃ Ａｃｉｄｓ Ｒｅｓ．， ２３［１２］（１９９５） ｐ．２２５９-２２６８
JPN6012016553; Ｄａｔａｂａｓｅ ＧｅｎＢａｎｋ ［ｏｎｌｉｎｅ］， Ａｃｃｅｓｓｉｏｎ Ｎｏ． Ｃ１２４７９１，＜ｈｔｔｐ：／／ｗｗｗ．ｎｃｂｉ．ｎｌｍ．ｎｉｈ．ｇｏｖ／ｎｕｃｃｏｒｅ／ＡＣ１２４７９１＞ １７-Ｊ
JPN5008014387; ＺＥＮＴＩＬＩＮ Ｌ．: ＣＵＲＲＥＮＴ ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ ＢＩＯＴＥＣＨＮＯＬＯＧＹ Ｖ５ Ｎ４, 200408, Ｐ３４１-３４７, ＢＥＮＴＨＡＭ ＳＣＩＥＮＣＥ ＰＵＢＬＩＳＨＥＲＳ
JPN6012016555; Ｏｒａｌ Ｏｎｃｏｌ．， ４１［７］（２００５-０８） ｐ．７１６-７２２
JPN6012016552; Ｎｕｃｌｅｉｃ Ａｃｉｄｓ Ｒｅｓ．， ２３［１２］（１９９５） ｐ．２２５９-２２６８
JPN6012016553; Ｄａｔａｂａｓｅ ＧｅｎＢａｎｋ ［ｏｎｌｉｎｅ］， Ａｃｃｅｓｓｉｏｎ Ｎｏ． Ｃ１２４７９１，＜ｈｔｔｐ：／／ｗｗｗ．ｎｃｂｉ．ｎｌｍ．ｎｉｈ．ｇｏｖ／ｎｕｃｃｏｒｅ／ＡＣ１２４７９１＞ １７-Ｊ
Attorney, Agent or Firm:
Masatake Shiga
Takashi Watanabe
Yasuhiko Murayama
Shinya Mitsuhiro
Takashi Watanabe
Yasuhiko Murayama
Shinya Mitsuhiro