Title:
アレルゲン性タンパク質の同定のためのインビトロアッセイ
Document Type and Number:
Japanese Patent JP2009508484
Kind Code:
A
Abstract:
The present invention relates to a process for in vitro evaluation of a potentially allergenic or tissue irritating substance whereby test cells are cultivated in the presence of the substance, and the presence of up regulated genes chosen from MT1G, MT1B;MT1A, MT1E, MT1F, MT1H, or expression products from them are measured. The invention also regards use of the expression products from one or more of the genes for in vitro analysis of allergy or tissue irritation. It also relates to a probe comprising at least three nucleic acids, preferably 3 - 40, especially 5 - 15 chosen from RNA complementary to the RNA corresponding to any of the genes and the use thereof for in vitro analysis of allergy or tissue irritation. Further it regards a reagent kit comprising one or more probes that recognize products produced during the expression of any the genes.
More Like This:
Inventors:
Karin Sederbrandt
Hannah Lundgren
Jan Torel
Hannah Lundgren
Jan Torel
Application Number:
JP2008531062A
Publication Date:
March 05, 2009
Filing Date:
September 14, 2006
Export Citation:
Assignee:
BIOVATOR TECHNOLOGIES AB
International Classes:
C12Q1/68; C12N15/09; C12Q1/02
Attorney, Agent or Firm:
Mitsuo Tanaka
Hiroshi Yamazaki
Michiko Matsutani
Mina Shiga
Sakurai Yoko
Satoshi Hashimoto
Hiroshi Yamazaki
Michiko Matsutani
Mina Shiga
Sakurai Yoko
Satoshi Hashimoto