Title:
疎水性親和性クロマトグラフィに基づく塩素化スクロースの生成方法
Document Type and Number:
Japanese Patent JP2009509925
Kind Code:
A
Abstract:
This invention relates to a process for selective capture, isolation and purification of chlorinated sucrose compounds, including chlorinated sucrose, their precursors and derivatives, including trichlorogalactosucrose (TGS), directly from chlorinated reaction mixture by column chromatography on adsorbents and under conditions which result in specific and selective affinity towards one or more of chlorinated sucrose compound. The process also integrates de-esterification of chlorinated sucrose esters adsorbed on the adsorbent while they are being treated with desorbent. The process also provides a novel approach to concentration and crystallization of TGS. The chlorinated sucrose derivatives, including TGS, thus isolated are substantially free from most impurities, salts and organic solvents. The process has high recovery of more than 95% in terms of desired chlorinated sucrose derivatives including TGS.
Inventors:
Ratnam Rakesh
Aurora Sundeep
Lari Alvind Marinas
Kale sandeep bashkar
Aurora Sundeep
Lari Alvind Marinas
Kale sandeep bashkar
Application Number:
JP2008528660A
Publication Date:
March 12, 2009
Filing Date:
August 29, 2006
Export Citation:
Assignee:
Farmed Medicare Private Limited
International Classes:
C07H5/02; B01D15/04; B01D15/08; B01J20/10; B01J20/26; B01J20/30; B01J49/00
Domestic Patent References:
| JP2001511812A | 2001-08-14 |
Foreign References:
| WO2003076454A1 | 2003-09-18 |
Attorney, Agent or Firm:
Junichi Omori
Ori Akira
Ori Akira