Title:
免疫反応を誘発する酵母ベースワクチン
Document Type and Number:
Japanese Patent JP2009528987
Kind Code:
A
Abstract:
A therapeutic composition comprising a yeast expressing at least one heterologous intracellular antigen from an infectious pathogen or a disease and at least one heterologous extracellular antigen from the pathogen or the disease wherein the intracellular antigen is a different antigen than the extracellular antigen, use of the compositions in eliciting an antigen-specific cell-mediated and/or humoral immune response in an individual or in treating or preventing infection with the pathogen or for treating or preventing the disease, and a method to produce a therapeutic composition for eliciting a cell-mediated and/or a humoral immune response against an infectious pathogen or a disease.
Inventors:
Duke, Richard, Sea.
Franz Soff, Alex
Haller, Aurelia
King, Thomas, H.
Le inn
Hudson, victorian, kelly
Franz Soff, Alex
Haller, Aurelia
King, Thomas, H.
Le inn
Hudson, victorian, kelly
Application Number:
JP2008553534A
Publication Date:
August 13, 2009
Filing Date:
February 02, 2007
Export Citation:
Assignee:
THE REGENTS OF THE UNIVERSITY OF COLORADO
International Classes:
A61K39/00; A61K36/06; A61K38/00; A61K39/145; A61K48/00; A61P31/16; A61P37/04; A61P43/00
Domestic Patent References:
| JP2006510718A | 2006-03-30 |
Other References:
JPN6012027235; ＶＡＣＣＩＮＥ ＶＯＬ．１９, 2001, Ｐ．３６８１-３６９１
JPN6012027237; ＡＰＰＬ．ＥＮＶＩＯＲＮ．ＭＩＣＲＯＢＩＯＬ． ＶＯＬ．６７， ＮＯ．５, 2001, Ｐ．２０８３-２０８７
JPN6012027237; ＡＰＰＬ．ＥＮＶＩＯＲＮ．ＭＩＣＲＯＢＩＯＬ． ＶＯＬ．６７， ＮＯ．５, 2001, Ｐ．２０８３-２０８７
Attorney, Agent or Firm:
Kenzo Hara International Patent Office