Title:
翻訳後修飾されたタンパク質の標識及び検出方法
Document Type and Number:
Japanese Patent JP2009528988
Kind Code:
A
Abstract:
The present invention generally relates to methods of functionalizing proteins, particularly antibodies, at oligosaccharide linkages, methods of humanizing antibodies by modifying glycosylation, as well as to novel antibodies linked to modified oligosaccharides. The invention further relates to kits that may be used to produce the antibodies of the invention.
Inventors:
Agnew Bryan
G-Kyle
Niberg Tamara
G-Kyle
Niberg Tamara
Application Number:
JP2008553858A
Publication Date:
August 13, 2009
Filing Date:
February 12, 2007
Export Citation:
Assignee:
Life Technologies Corporation
International Classes:
C07K17/00; A61K39/395; G01N27/447; C12P21/00
Foreign References:
| US20050130235A1 | 2005-06-16 |
Other References:
JPN6012035960; Ｔｈｅ Ｊｏｕｒｎａｌ ｏｆ Ｂｉｏｌｏｇｉｃａｌ Ｃｈｅｍｉｓｔｒｙ Ｖｏｌ．２７７， Ｎｏ．２３, 2002, ｐ．２０８３３-２０８３９
JPN6012035961; Ｂｉｏｏｒｇａｎｉｃ ａｎｄ Ｍｅｄｉｃｉｎａｌ Ｃｈｅｍｉｓｔｒｙ Ｖｏｌ．１３, 2005, ｐ．５０２１-５０３４
JPN6012035959; Ｊｏｕｒｎａｌ ｏｆ Ａｍｅｒｉｃａｎ Ｃｈｅｍｉｃａｌ Ｓｏｃｉｅｔｙ Ｖｏｌ．１２６， Ｎｏ．１, 2004, ｐ．６-７
JPN6012035961; Ｂｉｏｏｒｇａｎｉｃ ａｎｄ Ｍｅｄｉｃｉｎａｌ Ｃｈｅｍｉｓｔｒｙ Ｖｏｌ．１３, 2005, ｐ．５０２１-５０３４
JPN6012035959; Ｊｏｕｒｎａｌ ｏｆ Ａｍｅｒｉｃａｎ Ｃｈｅｍｉｃａｌ Ｓｏｃｉｅｔｙ Ｖｏｌ．１２６， Ｎｏ．１, 2004, ｐ．６-７
Attorney, Agent or Firm:
Hatsushi Shimizu
Toshi Gobe
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Ryuichi Inoue
Masato Ozeki
Toshi Gobe
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Ryuichi Inoue
Masato Ozeki