Title:
プロスタグランジンE2拮抗薬としてのアゼチジン誘導体およびその使用
Document Type and Number:
Japanese Patent JP2010526801
Kind Code:
A
Abstract:
The invention relates to EP2 antagonist azetidines of formula (I) wherein Ar, R1, X, and Z are as defined herein, to their use in medicine, particularly in the treatment of endometriosis and/or uterine fibroids, to intermediates useful in their synthesis, and to compositions containing them.
Inventors:
Kevin Nail Duck
Siew Kyung
Sarah Elizabeth Skelat
Siew Kyung
Sarah Elizabeth Skelat
Application Number:
JP2010507013A
Publication Date:
August 05, 2010
Filing Date:
April 28, 2008
Export Citation:
Assignee:
Pfizer Limited
International Classes:
C07D205/04; A61K31/397; A61K31/428; A61K31/4427; A61K31/4439; A61K31/444; A61K31/4709; A61K31/497; A61K31/501; A61K31/502; A61K31/506; A61P15/00; A61P15/08; A61P19/00; A61P29/00; A61P43/00; C07D401/12; C07D401/14; C07D403/12; C07D417/12; C07D417/14
Attorney, Agent or Firm:
Yoshinobu Murofushi
High Hoji Koji
Junko Miyazawa
Noh four
High Hoji Koji
Junko Miyazawa
Noh four