二環ヘテロアリール化合物およびそれらのキナーゼ阻害剤としての使用

Title:

二環ヘテロアリール化合物およびそれらのキナーゼ阻害剤としての使用

Document Type and Number:

Japanese Patent JP2010533680

Kind Code:

A

Abstract:

Phosphatidylinositol (PI) 3-kinase inhibitor compounds, their pharmaceutically acceptable salts, and prodrugs thereof; compositions of the new compounds, either alone or in combination with at least one additional therapeutic agent, with a pharmaceutically acceptable carrier; and uses of the new compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of proliferative diseases characterized by the abnormal activity of growth factors, protein serine/threonine kinases, and phospholipid kinases.

More Like This:

WO/2004/002531	REMEDIES FOR DISEASES CAUSED BY VASCULAR CONTRACTION OR DILATION
WO/2018/089355	CYCLOBUTANE- AND AZETIDINE-CONTAINING MONO AND SPIROCYCLIC COMPOUNDS AS ALPHA V INTEGRIN INHIBITORS
WO/2016/008593	NOVEL SUBSTITUTED PYRIMIDINE COMPOUNDS

Inventors:

Ian Bruce
Darren Mark Legrand
James Dale
Thomas Anthony Hunt

Application Number:

JP2010516500A

Publication Date:

October 28, 2010

Filing Date:

July 16, 2008

Export Citation:

Click for automatic bibliography generation Help

Assignee:

Novartis Age

International Classes:

C07D471/04; A61K31/437; A61K31/444; A61K31/4709; A61K31/4725; A61K31/4985; A61K31/506; A61K31/5377; A61P1/04; A61P3/04; A61P3/10; A61P9/00; A61P9/10; A61P11/00; A61P17/06; A61P19/02; A61P29/00; A61P31/00; A61P35/00; A61P37/00; A61P37/06; C07D487/04

Attorney, Agent or Firm:

Mitsuo Tanaka
Takuji Yamada
Mitsutaka Iwasaki
Aoyama Aoi
Masayuki Nakagawa
Yasushi Ochiai

Previous Patent: ＶＲ−１アンタゴニストとＣＯＸ−２阻害剤との相乗的組合せ剤

Next Patent: プレガバリンのエナンチオ選択的製造方法