Title:
糖尿病性腎症のための医薬組成物、並びにその調製及び適用
Document Type and Number:
Japanese Patent JP2011510098
Kind Code:
A
Abstract:
The invention relates to a pharmaceutical composition for diabetic nephropathy and its preparation, and the application in preparing of medicine for diabetic nephropathy. The pharmaceutical composition is made up of at least one of 7-hydroxycoumarin and 7-hydroxy-6-methoxycoumarin as active ingredient, and the weight percentage of active ingredient is 0.1-99.5%. Moreover, the pharmaceutical composition is mainly used for the prevention and cure of diabetic nephropathy. For the abundant material, remarkable effect on prevention and cure for diabetic nephropathy and convenience for use, it will be a new facultative drug for patients.
Inventors:
Zhu, Gwang
Shih, Shinhwa
Tan, Dan
Zhen, Zhaoguan
F, Bao
Duane, Tintin
Guy, Faye
Chen, Hoi Kuang
Xuan Lin
Juan, Yancia
Wang, Lushan
Shih, Shinhwa
Tan, Dan
Zhen, Zhaoguan
F, Bao
Duane, Tintin
Guy, Faye
Chen, Hoi Kuang
Xuan Lin
Juan, Yancia
Wang, Lushan
Application Number:
JP2010546200A
Publication Date:
March 31, 2011
Filing Date:
March 31, 2009
Export Citation:
Assignee:
GUANGZHOU CONSUN MEDICINE R & D Co.,LTD.
International Classes:
A61K31/37; A61K9/08; A61K9/14; A61K9/20; A61K9/48; A61K47/02; A61K47/10; A61K47/12; A61K47/18; A61K47/26; A61K47/32; A61K47/34; A61K47/36; A61K47/42; A61P13/12
Other References:
JPN6012050187; ＲＡＭＥＳＨ，Ｂ． ｅｔ ａｌ: 'Ｐｒｏｔｅｃｔｉｖｅ ｅｆｆｅｃｔ ｏｆ Ｕｍｂｅｌｌｉｆｅｒｏｎｅ ｏｎ ｍｅｍｂｒａｎｏｕｓ ｆａｔｔｙ ａｃｉｄ ｃｏｍｐｏｓｉｔｉｏｎ ｉｎ ｓｔｒｅｐｔｏｚｏｔｏｃｉｎ-ｉｎｄｕｃｅｄ ｄｉ' ＥＵＲＯＰＥＡＮ ＪＯＵＲＮＡＬ ＯＦ ＰＨＡＲＭＡＣＯＬＯＧＹ Ｖｏｌ．５６６， Ｎｏ．１-３, 2007, ｐ．２３１-２３９
JPN6012050190; ＲＡＭＥＳＨ，Ｂ． ｅｔ ａｌ: 'Ｅｆｆｅｃｔ ｏｆ ｕｍｂｅｌｌｉｆｅｒｏｎｅ ｏｎ ｔａｉｌ ｔｅｎｄｏｎ ｃｏｌｌａｇｅｎ ａｎｄ ｈａｅｍｏｓｔａｔｉｃ ｆｕｎｃｔｉｏｎ ｉｎ ｓｔｒｅｐｔｏｚｏｔｏｃｉｎ-ｄｉａｂｅｔｉｃ' Ｂａｓｉｃ ＆ Ｃｌｉｎｉｃａｌ Ｐｈａｒｍａｃｏｌｏｇｙ ＆ Ｔｏｘｉｃｏｌｏｇｙ Ｖｏｌ．１０１， Ｎｏ．２, 2007, ｐ．７３-７７
JPN6012050191; ＯＫＡＤＡ，Ｙ． ｅｔ ａｌ: 'Ｓｅａｒｃｈ ｆｏｒ Ｎａｔｕｒａｌｌｙ Ｏｃｃｕｒｒｉｎｇ Ｓｕｂｓｔａｎｃｅｓ ｔｏ Ｐｒｅｖｅｎｔ ｔｈｅ Ｃｏｍｐｌｉｃａｔｉｏｎｓ ｏｆ Ｄｉａｂｅｔｅｓ． ＩＩ． Ｉｎｈｉｂｉｔｏｒｙ Ｅ' Ｃｈｅｍｉｃａｌ ＆ ｐｈａｒｍａｃｅｕｔｉｃａｌ ｂｕｌｌｅｔｉｎ Ｖｏｌ．４３， Ｎｏ．８, 1995, ｐ．１３８５-１３８７
JPN6012050190; ＲＡＭＥＳＨ，Ｂ． ｅｔ ａｌ: 'Ｅｆｆｅｃｔ ｏｆ ｕｍｂｅｌｌｉｆｅｒｏｎｅ ｏｎ ｔａｉｌ ｔｅｎｄｏｎ ｃｏｌｌａｇｅｎ ａｎｄ ｈａｅｍｏｓｔａｔｉｃ ｆｕｎｃｔｉｏｎ ｉｎ ｓｔｒｅｐｔｏｚｏｔｏｃｉｎ-ｄｉａｂｅｔｉｃ' Ｂａｓｉｃ ＆ Ｃｌｉｎｉｃａｌ Ｐｈａｒｍａｃｏｌｏｇｙ ＆ Ｔｏｘｉｃｏｌｏｇｙ Ｖｏｌ．１０１， Ｎｏ．２, 2007, ｐ．７３-７７
JPN6012050191; ＯＫＡＤＡ，Ｙ． ｅｔ ａｌ: 'Ｓｅａｒｃｈ ｆｏｒ Ｎａｔｕｒａｌｌｙ Ｏｃｃｕｒｒｉｎｇ Ｓｕｂｓｔａｎｃｅｓ ｔｏ Ｐｒｅｖｅｎｔ ｔｈｅ Ｃｏｍｐｌｉｃａｔｉｏｎｓ ｏｆ Ｄｉａｂｅｔｅｓ． ＩＩ． Ｉｎｈｉｂｉｔｏｒｙ Ｅ' Ｃｈｅｍｉｃａｌ ＆ ｐｈａｒｍａｃｅｕｔｉｃａｌ ｂｕｌｌｅｔｉｎ Ｖｏｌ．４３， Ｎｏ．８, 1995, ｐ．１３８５-１３８７
Attorney, Agent or Firm:
Isshiki International Patent Service Corporation