Title:
有機酸保存剤と組み合わせた安息香酸を活性構成成分として含む組成物、およびその使用
Document Type and Number:
Japanese Patent JP2013507328
Kind Code:
A
Abstract:
The present invention relates to the use of low content of benzoic acid and/or sodium salt thereof in combination with one or more organic acid preservatives as active ingredients in the manufacture of a vaginal composition, wherein the composition has weak inhibition effect on normal vaginal lactobacilli while has strong inhibition effect on vaginal fungi and/or pathogenic vaginal lactobacilli, the organic acid preservatives are selected from the group consisting of dehydroacetic acid and/or sodium salt thereof, propionic acid and/or a salt thereof, sorbic acid and/or a salt thereof. The composition of the present invention is particularly useful in inhibiting vaginal fungi, and/or inhibiting pathogenic vaginal lactobacilli, and/or promoting normal vaginal lactobacilli, and/or maintaining normal vaginal acidity, and/or modulating vaginal microecosystem, and/or modulating vaginal microbials, and/or selectively decontaminating vagina.
Inventors:
ZENG, ZHONGMING
ZHOU, RUYUN
ZHOU, RUYUN
Application Number:
JP2012532442A
Publication Date:
March 04, 2013
Filing Date:
October 08, 2010
Export Citation:
Assignee:
ZENG, ZHONGMING
ZHOU, RUYUN
PHLORA BIO-TECHNOLOGY INVESTMENT LIMITED
ZHOU, RUYUN
PHLORA BIO-TECHNOLOGY INVESTMENT LIMITED
International Classes:
A61K31/192; A61K8/36; A61K8/368; A61K8/49; A61K31/19; A61K31/191; A61K31/366; A61P15/02; A61P29/00; A61P31/04; A61P31/10; A61Q15/00; A61Q19/00; A61Q19/10
Domestic Patent References:
| JP2009167139A | 2009-07-30 | |||
| JP2008539176A | 2008-11-13 | |||
| JPH06508612A | 1994-09-29 | |||
| JPH05262631A | 1993-10-12 |
Other References:
JPN6014034811; ＢＩＯ ＲＥＶＩＥＷ Ｖｏｌ．９， Ｎｏ．３, 1992, ｐ．２３-４５
Attorney, Agent or Firm:
Yasunori Otsuka
Shiro Takayanagi
Yasuhiro Otsuka
Shuji Kimura
Osamu Shimoyama
Shiro Takayanagi
Yasuhiro Otsuka
Shuji Kimura
Osamu Shimoyama