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Title:
悪性腫瘍の治療のための免疫活性化血液灌流フィルタ
Document Type and Number:
Japanese Patent JP2013507379
Kind Code:
A
Abstract:
The invention provides a way of producing a natural immunologically active state in a person by subjecting him to an apheresis procedure with bioincompatible biomaterials for about one hour. To safely control the immunological shock induced by this procedure, the person is put under general anesthesia for about six hours, including the apheresis time and at least an additional five hours thereafter. This immunological activation is useful for treating malignant tumors and diseases related to immunosuppression, such as AIDS. The invention also provides for the use of an apheresis column containing a blood perfusion filter with bioincompatible materials for treating malignant tumors and infectious diseases.

Inventors:
Nosehiko Nose
Kazuhide Ota
Hiroshi Miyamoto
Junji Takaba
Application Number:
JP2012533319A
Publication Date:
March 04, 2013
Filing Date:
October 07, 2010
Export Citation:
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Assignee:
Otsuka Pharmaceutical Co., Ltd.
International Classes:
A61K35/14; A61M1/02; A61M1/36; A61P1/16; A61P31/00; A61P31/18; A61P35/00; A61P37/04
Domestic Patent References:
JP2005304647A2005-11-04
JPS5359017A1978-05-27
JPH01124382A1989-05-17
Foreign References:
WO2006073106A12006-07-13
Other References:
JPN6015011363; 臨床透析 15(6), 1999, p.667-673
JPN6014044283; Transfus.Sci. Vol.17,No.3, 1996, p.463-472
JPN6015011353; 炎症 20(5), 2000, p.613-617
JPN6015011354; 病院薬学 16(6), 1990, p.366-371
JPN6015011356; Journal of Clinical Apheresis 5, 1989, p.7-11
JPN6015011358; 薬学雑誌 98(4), 1978, p.489-494
JPN6015011360; Anticancer Research 15, 1995, p.985-990
JPN6015011362; 臨床血液 26(11), 1985, p.1885-1891
Attorney, Agent or Firm:
Patent Business Corporation Saegusa International Patent Office