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Title:
加齢黄斑変性における遺伝的多型性
Document Type and Number:
Japanese Patent JP2013507963
Kind Code:
A
Abstract:
The application relates to methods for determining whether a patient is at increased risk of developing wet AMD or whether a patient has an increased likelihood of benefiting from treatment with a high-affinity anti-VEGF antibody.

Inventors:
Robert Graham
Application Number:
JP2012535329A
Publication Date:
March 07, 2013
Filing Date:
October 20, 2010
Export Citation:
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Assignee:
Genentech, Incorporated
International Classes:
C12Q1/68; A61K39/395; A61P27/02; C12N15/09
Other References:
JPN5012017939; LEE A Y: 'PHARMACOGENETICS OF COMPLEMENT FACTOR H(Y402H) AND TREATMENT 以下備考' BRITISH JOURNAL OF OPHTHALMOLOGY V93 N5, 20090501, P610-613
JPN5012017940; KLEIN ROBERT J: 'COMPLEMENT FACTOR H POLYMORPHISM IN AGE-RELATED MACULAR DEGENERATION' SCIENCE V308 N5720, 20050415, P385-389
JPN5012017939; LEE A Y: 'PHARMACOGENETICS OF COMPLEMENT FACTOR H(Y402H) AND TREATMENT 以下備考' BRITISH JOURNAL OF OPHTHALMOLOGY V93 N5, 20090501, P610-613
JPN5012017940; KLEIN ROBERT J: 'COMPLEMENT FACTOR H POLYMORPHISM IN AGE-RELATED MACULAR DEGENERATION' SCIENCE V308 N5720, 20050415, P385-389
Attorney, Agent or Firm:
Sonoda Yoshitaka
Kobayashi Yoshinori