Title:
単一分子全ゲノム解析のための方法及び関連装置
Document Type and Number:
Japanese Patent JP2013507964
Kind Code:
A
Abstract:
Provided are methods of labeling and analyzing features along at least one macromolecule such as a linear biopolymer, including methods of mapping the distribution and frequency of specific sequence motifs or the chemical or proteomic modification state of such sequence motifs along individual unfolded nucleic acid molecules. The present invention also provides methods of identifying signature patterns of sequence or epigenetic variations along such labeled macromolecules for direct massive parallel single molecule level analysis. The present invention also provides systems suitable for high throughput analysis of such labeled macromolecules.
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Inventors:
Xiao, Ming
Das, Somekumaru
Das, Somekumaru
Application Number:
JP2012535362A
Publication Date:
March 07, 2013
Filing Date:
October 21, 2010
Export Citation:
Assignee:
Bionano genomics, ink.
International Classes:
C12Q1/68; C12M1/34; C12N15/09
Attorney, Agent or Firm:
Taro Yaguchi
Junichiro Yanagi
Junichiro Yanagi