Title:
アリール置換インドールおよびその使用
Document Type and Number:
Japanese Patent JP2013530180
Kind Code:
A
Abstract:
The invention relates to aryl and heteroaryl substituted compounds of Formula (I), and pharmaceutically acceptable salts, prodrugs, or solvates thereof, wherein G, R1, and Z1-Z5 are defined as set forth in the specification. The invention is also directed to the use of compounds of Formula (I) to treat a disorder responsive to the blockade of sodium channels. Compounds of the present invention are especially useful for treating pain.
More Like This:
Inventors:
Kire, Donald, Jay.
D, Chiyo
Tafese, Ray Care
Yao, Jiang Chao
D, Chiyo
Tafese, Ray Care
Yao, Jiang Chao
Application Number:
JP2013514796A
Publication Date:
July 25, 2013
Filing Date:
June 16, 2011
Export Citation:
Assignee:
PURDUE PHARMA L.P.
International Classes:
C07D209/12; A61K31/404; A61K31/4045; A61K31/405; A61K31/416; A61K31/437; A61K31/4439; A61P9/06; A61P9/10; A61P25/02; A61P25/04; A61P25/06; A61P25/08; A61P25/18; A61P25/24; A61P25/28; A61P27/16; C07D209/16; C07D209/18; C07D231/56; C07D401/12; C07D471/04; G01N33/15; G01N33/50; G01N33/536; G01N33/566
Domestic Patent References:
| JP2003528859A | 2003-09-30 | |||
| JP2006504660A | 2006-02-09 | |||
| JP2009539913A | 2009-11-19 | |||
| JP2007502257A | 2007-02-08 |
Foreign References:
| WO2008133867A1 | 2008-11-06 |
Other References:
JPN6014011738; Ｔｏｍ Ｙ． Ｈ． Ｗｕ ｅｔ ａｌ: 'Ａ Ｖｅｒｓａｔｉｌｅ Ｌｉｎｋａｇｅ Ｓｔｒａｔｅｇｙ ｆｏｒ Ｓｏｌｉｄ-Ｐｈａｓｅ Ｓｙｎｔｈｅｓｉｓ ｏｆ Ｎ，Ｎ-Ｄｉｍｅｔｈｙｌｔｒｙｐｔａｍｉｎｅｓ ａｎｄ beta-Ｃａｒｂｏｌｉｎｅｓ' Ｏｒｇａｎｉｃ Ｌｅｔｔｅｒｓ Ｖｏｌ．４， Ｎｏ．２３, 2002, ｐ．４０３３-４０３６
Attorney, Agent or Firm:
Hiroshi Kobayashi
Norio Omori
Kyoei Sugiyama
Yasuhito Suzuki
Norio Omori
Kyoei Sugiyama
Yasuhito Suzuki