Title:
増殖性疾患を処置するための組み合わせ療法
Document Type and Number:
Japanese Patent JP2013533232
Kind Code:
A
Abstract:
The invention provides a composition comprising nanoparticles comprising a taxane and a carrier protein for use in a method of treating a proliferative disease in an individual, wherein the method further comprises administering to the individual at least one other agent that inhibits a DNA methyltransferase. The invention further provides a kit and a medicine comprising a composition comprising nanoparticles comprising a taxane and a carrier protein, and at least one other agent that inhibits a DNA methyltransferase.
Inventors:
Desai, Neil Pee.
Soon-Sion, Patrick
Soon-Sion, Patrick
Application Number:
JP2013514194A
Publication Date:
August 22, 2013
Filing Date:
May 20, 2011
Export Citation:
Assignee:
Abraxis Bioscience, LLC
International Classes:
A61K31/337; A61K9/14; A61K31/167; A61K31/282; A61K31/706; A61K45/00; A61K47/42; A61P11/00; A61P15/00; A61P35/00; A61P43/00; C12N15/09
Domestic Patent References:
| JP2002507976A | 2002-03-12 | |||
| JP2010511702A | 2010-04-15 | |||
| JP2004529104A | 2004-09-24 | |||
| JP2009514879A | 2009-04-09 | |||
| JP2007524650A | 2007-08-30 | |||
| JP2008530248A | 2008-08-07 | |||
| JP2010509331A | 2010-03-25 |
Foreign References:
| WO2009139888A1 | 2009-11-19 | |||
| WO2008028193A2 | 2008-03-06 |
Other References:
JOURNAL OF NEUROCHEMISTRY, vol. Vol.108, Suppl.1, JPN6015021233, March 2009 (2009-03-01), pages 116 - 09, ISSN: 0003084571
NATURE, vol. 455, JPN6015021238, 2008, pages 1023 - 1028, ISSN: 0003084576
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CLINICAL BREAST CANCER, vol. 10, no. 1, JPN6015021237, February 2010 (2010-02-01), pages 81 - 86, ISSN: 0003084575
NATURE, vol. 455, JPN6015021238, 2008, pages 1023 - 1028, ISSN: 0003084576
JOURNAL OF CLINICAL ONCOLOGY, vol. 28, no. 1, JPN6015021234, January 2010 (2010-01-01), pages 56 - 62, ISSN: 0003084572
BREAST CANCER RES TREAT, vol. 125, JPN6015021235, 2011, pages 55 - 63, ISSN: 0003084573
ONCOTARGETS AND THERAPY, JPN6015021236, July 2009 (2009-07-01), pages 179 - 188, ISSN: 0003084574
CLINICAL BREAST CANCER, vol. 10, no. 1, JPN6015021237, February 2010 (2010-02-01), pages 81 - 86, ISSN: 0003084575
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Natsuki Morishita