Title:
プレキシンB2活性の変調剤
Document Type and Number:
Japanese Patent JP2014516922
Kind Code:
A
Abstract:
Disclosed herein are novel compositions and methods for the inhibition of Plexin B2-mediated Angiogenin activity. Such compositions and methods are useful, for example, for the treatment of cancer, the treatment of wet AMD and the inhibition of angiogenesis. Also disclosed herein are methods of determining whether a test agent is a modulator of Plexin B2 activity.
Inventors:
Huh, Guohu
Yui, Wenhao
Yui, Wenhao
Application Number:
JP2014502745A
Publication Date:
July 17, 2014
Filing Date:
March 28, 2012
Export Citation:
Assignee:
PRESIDENT AND FELLOWS OFHARVARD COLLEGE
TUFTS MEDICAL CENTER,INC.
TUFTS MEDICAL CENTER,INC.
International Classes:
C07K16/28; A61K38/00; A61K39/395; A61P9/00; A61P27/02; A61P35/00; C07K14/71; C07K16/46; C12N15/02; C12N15/113; G01N33/15; G01N33/50; C12P21/08
Attorney, Agent or Firm:
Yanagita Seiji
Go Sakuma
Go Sakuma