Title:
【発明の名称】自己免疫性を改善せしめるうえで有用なMHCコンジュゲート
Document Type and Number:
Japanese Patent JP3487849
Kind Code:
B2
Abstract:
The present invention is directed to complexes consisting essentially of an isolated MHC component and an autoantigenic peptide associated with the antigen binding site of the MHC component. These complexes are useful in treating autoimmune disease.
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Inventors:
Clark, Brian Earl.
Sharma, Somesh Dee.
Larch, Bernard El.
Sharma, Somesh Dee.
Larch, Bernard El.
Application Number:
JP51142492A
Publication Date:
January 19, 2004
Filing Date:
April 23, 1992
Export Citation:
Assignee:
Coulter Pharmaceutical, Incorporated
International Classes:
A61K39/00; A61K39/385; A61K47/48; A61K51/12; A61P19/02; A61P21/04; A61P29/00; A61P37/00; A61P37/02; A61P37/06; C07K14/47; C07K14/705; C07K14/74; C07K14/78; C07K19/00; (IPC1-7): A61K39/00; A61K39/385; A61P19/02; A61P21/04; A61P29/00; A61P37/02; A61P37/06; C07K14/705; C07K14/74; C07K19/00
Other References:
【文献】国際公開89/012459(WO,A1)
【文献】KUMAR, V., et al., Amino acid variations at a sing
【文献】OTA, K., et al., T-cell recognition of an immunodo
【文献】KUMAR, V., et al., Amino acid variations at a sing
【文献】OTA, K., et al., T-cell recognition of an immunodo
Attorney, Agent or Firm:
Shusaku Yamamoto (2 outside)