短時間作用型ジヒドロピリジン類

Japanese Patent JP3712209

B2

PCT No. PCT/SE94/01031 Sec. 371 Date Dec. 14, 1994 Sec. 102(e) Date Dec. 14, 1994 PCT Filed Nov. 3, 1994 PCT Pub. No. WO95/12578 PCT Pub. Date May 11, 1995Compounds of the general formula I wherein R1 and R2 are independently selected from the group consisting of hydrogen, chloro, bromo, nitro, cyano, trifluoromethyl, and R3 and R4 are independently selected from straight or branched lower (1-5 carbon atoms) alkyl groups, and including all optical isomers, provided that when R3 is methyl and R4 is tert.-butyl, then R1/R2 are not hydrogen/hydrogen, hydrogen/2'-trifluormethyl, 2'-chloro/3'-chloro, and when R3 is methyl and R1/R2 is hydrogen/3'-nitro, then R4 are not methyl, ethyl, propyl, iso-propyl, tert.-butyl, processes for their preparation, pharmaceutical preparations containing them and the use of the compounds in lowering the blood pressure.

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JP4971794	How to reduce amyloid deposits, amyloid neurotoxicity and microgliosis

Ardellson, Ciel Jarmar
Nordlander, Margareta
Wosterlund, Rolf Christel

JP51317095A

November 02, 2005

November 03, 1994

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ASTRAZENECA AKTIEBOLAG

A61K31/44; A61K31/4422; A61P9/12; C07D211/90; (IPC1-7): C07D211/90; A61K31/4422; A61P9/12

JP5564571A

Tetrahedron Letters, 1991年,Vol.32, No.41, p.5805-5808
Tetrahedron Letters, 1992年,Vol.33, No.47, p.7157-7160

Chika Takagi
Tatsuo Sato
Kosuke Nishimura

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