Title:
環状ポリアミン
Document Type and Number:
Japanese Patent JP3749253
Kind Code:
B2
Abstract:
PCT No. PCT/GB95/00019 Sec. 371 Date Jun. 20, 1996 Sec. 102(e) Date Jun. 20, 1996 PCT Filed Jan. 6, 1995 PCT Pub. No. WO95/18808 PCT Pub. Date Jul. 13, 1995Linked polyamine cyclic compounds of general formula V-R-A-R'-W where V and W are independently cyclic polyamine moieties having from 9 to 32 ring members and 3 to 8 amine nitrogens and having either one or more aromatic rings fused thereto or a heteroatom other than nitrogen incorporated in the ring, A is an aliphatic or aromatic moiety and R and R' are each a linking chain, possess improved partition coefficients at biologically relevant pH compared to known compounds, and possess high anti-HIV activity.
Inventors:
Brigger, gray, james
Pamanavan, Three Nivasan
Scaleju, Renato Tony
Pamanavan, Three Nivasan
Scaleju, Renato Tony
Application Number:
JP51837095A
Publication Date:
February 22, 2006
Filing Date:
January 06, 1995
Export Citation:
Assignee:
Anomed Incorporated
International Classes:
A61K31/395; C07D519/00; A61K31/439; A61P31/12; A61P31/18; C07D273/00
Domestic Patent References:
| JP2104588A |
Foreign References:
| WO1993012096A1 | ||||
| EP0434385A1 |
Other References:
Inorganica Chimica Acta, 1993年,Vol.204, No.2 , p.267-9
Bulletin of the Chemical Society of Japan, 1990年,Vol.63, No.6, p.1587-91
Inorganica Chimica Acta, 1983年,Vol.75, No.2, p.169-71
Bulletin of the Chemical Society of Japan, 1990年,Vol.63, No.6, p.1587-91
Inorganica Chimica Acta, 1983年,Vol.75, No.2, p.169-71
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Tetsuji Koga
Kazuhiro Nakamura
Masaya Nishiyama
Takashi Ishida
Tetsuji Koga
Kazuhiro Nakamura
Masaya Nishiyama