安定な医薬組成物 - Sumitomo Dainippon Pharma Co., Ltd.

Title:

安定な医薬組成物

Document Type and Number:

Japanese Patent JP3995414

Kind Code:

B2

Abstract:

A stabilized pharmaceutical composition comprising (R)-2-(4-bromo-2-fluorobenzyl)-1,2,3,4-tetrahydropyrrolo-Ä1,2-aÜpyrazi ne-4-spiro-3'-pyrrolidine-1,2',3,5'-tetrone (hereinafter, referred to as "AS-3201") and as a stabilizer at least one acidic substance having an acidity more potent than that of AS-3201, such as ascorbic acid, citric acid, tartaric acid, lactic acid, maleic acid, malic acid or phosphoric acid.

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Inventors:

Ohashi Mamoru
Ichikatsu Ogasawara
Shirai Hisami
Hiroshi Fujioka

Application Number:

JP2000516673A

Publication Date:

October 24, 2007

Filing Date:

October 15, 1998

Export Citation:

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Assignee:

Sumitomo Dainippon Pharma Co., Ltd.

International Classes:

A61K31/499; A61K47/12; A61K47/24

Domestic Patent References:

JP5186472A
JP6192222A
JP8176105A

Other References:

医薬品添加物研究会編,「実用医薬品添加物」,1974年,p.215-217,258-259

Attorney, Agent or Firm:

Aoyama Aoi
Kyousei Tamura

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