Title:
C型肝炎ウイルスの検出のための試薬および方法
Document Type and Number:
Japanese Patent JP4164098
Kind Code:
B2
Abstract:
The invention provides oligonucleotide probes for detecting hepatitis C virus nucleic acids from the U.S., Japan, and HCV-C prototype strains, as well as oligonucleotide primers for amplifying such nucleic acids. The invention also provides methods and kits for amplifying and detecting said nucleic acids. The amplification methods preferably include the reverse transcription of the viral genomic RNA to create cDNA and the subsequent amplification of the cDNA by the polymerase chain reaction. Oligonucleotide probes can then be used to detect the presence of amplified DNA by hybridization.
Inventors:
Robert M. Resnick
Karen Kay Wy Young
Karen Kay Wy Young
Application Number:
JP2006042214A
Publication Date:
October 08, 2008
Filing Date:
February 20, 2006
Export Citation:
Assignee:
F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT
International Classes:
C12N7/00; C07K14/18; C12Q1/68; C12N15/09; C12N15/51; C12Q1/70
Domestic Patent References:
| JP3790274B2 |
Other References:
Lancet,1990年,vol.336,p.245
Jpn. J. Exp. Med.,1990年,vol.60,p.215-222
Jpn. J. Exp. Med.,1990年,vol.60,p.167-177
J. Gen. Virol.,1990年,vol.71,p.3027-3033
Proc. Natl. Acad. Sci. USA,1991年 3月,vol.88,p.1711-1715
Jpn. J. Exp. Med.,1990年,vol.60,p.215-222
Jpn. J. Exp. Med.,1990年,vol.60,p.167-177
J. Gen. Virol.,1990年,vol.71,p.3027-3033
Proc. Natl. Acad. Sci. USA,1991年 3月,vol.88,p.1711-1715
Attorney, Agent or Firm:
Hideto Asamura
Hajime Asamura
Naganuma Akio
Hajime Asamura
Naganuma Akio