Title:
ムンバイスタチン、その製造法およびその医薬としての使用
Document Type and Number:
Japanese Patent JP4287593
Kind Code:
B2
Abstract:
The present invention relates to a compound named Mumbaistatin, its pharmaceutically acceptable salts and derivatives, a process for its production, and its use as a pharmaceutical. Mumbaistatin is obtainable by cultivation of the microorganism HIL-008003 (DSM 11641). Mumbaistatin is a glucose-6-phosphate translocase inhibitor and can be used in the treatment of diabetes mellitus. The present invention further relates to a process for the production of Mumbaistatin, to the microorganism HIL-008003 (DSM 11641), to the use of Mumbaistatin and its pharmaceutically acceptable salts and derivatives as pharmaceuticals, in particular to their use in the treatment of diabetes mellitus, and to pharmaceutical compositions comprising Mumbaistatin or a pharmaceutically acceptable salt or derivative thereof.
Inventors:
Nilogi Venkata Sacha Ramakrishna
Keshavapura, Hosamane, Sledhara, Swami
Ella Koteswara Sacha Vijaya Kumar
Manoi Maniram Shin Kushwaha
Slevi Coater
Missiri Rahman
Swati Dernanjay Thale
Sunil Kumar Deshmuuk
Dietmar Schumer
Michael Kurz
Herbert Kogler
Keshavapura, Hosamane, Sledhara, Swami
Ella Koteswara Sacha Vijaya Kumar
Manoi Maniram Shin Kushwaha
Slevi Coater
Missiri Rahman
Swati Dernanjay Thale
Sunil Kumar Deshmuuk
Dietmar Schumer
Michael Kurz
Herbert Kogler
Application Number:
JP2000556048A
Publication Date:
July 01, 2009
Filing Date:
June 15, 1999
Export Citation:
Assignee:
Sanofi-Aventis Deutschland Gesellschaft Mitt Beschlenktel Haftung
International Classes:
A61K31/00; C12N9/99; A61K35/74; C12P15/00; A61P3/10; A61P43/00; C07G99/00; C12N1/14; C12N1/20; C12P1/04; C12P1/06; C12P7/02; C12P7/24; C12P7/66; C12R1/465
Other References:
J.Antibiot.,Vol.54,No.4(2001)p.354-363
Attorney, Agent or Firm:
Chika Takagi
Kosuke Nishimura
Kosuke Nishimura