Title:
微生物触媒を用いたアミド化合物の製造方法
Document Type and Number:
Japanese Patent JP4708677
Kind Code:
B2
Abstract:
This invention relates to a process for producing an amide compound from a nitrile compound using a microbial catalyst, wherein a microbial cell having nitrile hydratase activity of 50 U or higher per mg of dry cell at a reaction temperature of 10 DEG C is brought into contact with a nitrile compound in an aqueous medium without being immobilized. This method utilizes a microbial cell that exhibits high nitrile hydratase activity in the reaction without being entrap-immobilized. Thus, an amide compound can be effectively produced from a nitrile compound without problems of decreased reaction speed or lowered amount produced per unit cell amount, which are caused by entrap-immobilization. Accordingly, an amide compound can be produced within a very short period of time in the case of a batch reaction and with a very small-scale facility in the case of a continuous reaction.
Inventors:
Kozo Murao
Katsuo Ishii
Katsuo Ishii
Application Number:
JP2002551176A
Publication Date:
June 22, 2011
Filing Date:
December 19, 2001
Export Citation:
Assignee:
Dianitrix Co., Ltd.
International Classes:
C12P13/02; C12P17/12; C12R1/01
Domestic Patent References:
| JP2177883A |
Other References:
Appl.Microbiol.,Vol.40,1993,p.189-195
Attorney, Agent or Firm:
Yusuke Hiraki
Ishii Teiji
Ishii Teiji
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