Title:
体細胞核初期化物質のスクリーニング方法
Document Type and Number:
Japanese Patent JP4901471
Kind Code:
B2
Abstract:
The present invention provides a screening method for somatic cell nuclear reprogramming substances, which comprises (a) a step for bringing into contact with each other a somatic cell comprising a gene wherein a marker gene is present at a position permitting expression control by the expression control region of an ECAT gene, and a test substance, and (b) a step following the aforementioned step (a), for determining the presence or absence of the emergence of cells expressing the marker gene, and selecting a test substance allowing the emergence of the cells as a somatic cell nuclear reprogramming substance candidate, and the like.
Inventors:
Shinya Yamanaka
Application Number:
JP2006510284A
Publication Date:
March 21, 2012
Filing Date:
February 16, 2005
Export Citation:
Assignee:
Kyoto University
Sumitomo Dainippon Pharma Co., Ltd.
Sumitomo Dainippon Pharma Co., Ltd.
International Classes:
C07K14/47; C12Q1/68; C12N5/10; C12N15/09; C12Q1/02; G01N33/15; G01N33/50
Domestic Patent References:
| JP2002512787A | 2002-05-08 | |||
| JP2003506075A | 2003-02-18 |
Foreign References:
| WO2003027278A1 | 2003-04-03 | |||
| WO2003083089A2 | 2003-10-09 | |||
| WO2002097090A1 | 2002-12-05 | |||
| WO2003042384A1 | 2003-05-22 | |||
| WO2003095628A2 | 2003-11-20 | |||
| WO2002061033A2 | 2002-08-08 |
Attorney, Agent or Firm:
Takashima Ichi
Yobe
Yobe
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