Title:
Gタンパク質共役受容体RCC356の天然リガンドおよびその使用
Document Type and Number:
Japanese Patent JP5307404
Kind Code:
B2
Abstract:
The invention relates to the identification of isovaleric acid as a natural ligand of the RCC356 G-protein coupled receptor (GPCR). The invention encompasses the use of the interaction of RCC356 polypeptides and isovaleric acid as the basis of screening assays for agents that modulate the activity of the RCC356 receptor. The invention also encompasses diagnostic and other assays performed based upon the RCC356/isovaleric acid interaction, as well as kits for performing diagnostic and screening assays.
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Inventors:
Frederick Salman
Weissen, Alex
Philippe, Magari
Weissen, Alex
Philippe, Magari
Application Number:
JP2007557423A
Publication Date:
October 02, 2013
Filing Date:
March 02, 2006
Export Citation:
Assignee:
Chemicom S.A.
International Classes:
C12Q1/68; A61K31/19; A61K39/395; A61K45/00; A61P25/00; A61P25/08; A61P35/00; A61P35/04; C07K16/28; C12N15/00; C12Q1/02; C12Q1/42; C12Q1/48; C12Q1/527; C12Q1/70; G01N33/15; G01N33/50; A01K67/027; C07K14/705
Domestic Patent References:
| JP2003511029A |
Foreign References:
| WO2003057730A1 |
Other References:
Vanti WB et al.,Novel human G-protein-coupled receptors.,Biochem Biophys Res Commun.,2003年 5月23日,305(1),67-71
Attorney, Agent or Firm:
Takashi Shoji
Yuriko Shinobu
Takuya Osugi
Yuriko Shinobu
Takuya Osugi
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