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Title:
CGRP受容体アンタゴニスト
Document Type and Number:
Japanese Patent JP5382799
Kind Code:
B2
Abstract:
The present invention relates to CGRP receptor antagonists, pharmaceutical compositions thereof, and methods therewith for treating CGRP receptor-mediated diseases and conditions. The present invention relates to CGRP receptor antagonists of formula 1, wherein: X is S, SO, or SO2; pharmaceutical compositions thereof, and methods therewith for treating CGRP receptor-mediated diseases and conditions.

Inventors:
Gutierrez, Collie
Termin, Andreas
Hadida Rua, Sara
Joshi, Pramod
Bergeron, Daniel
Yo, sanhee
Vinci, Haley
Cam, john
Nanta Kumar, Suganti
Khao, Chinglong
Application Number:
JP2009515476A
Publication Date:
January 08, 2014
Filing Date:
June 13, 2007
Export Citation:
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Assignee:
VERTEX PHARMACEUTICALS INCORPORATED
International Classes:
C07D417/14; A61K31/438; A61K31/4545; A61K31/517; A61K31/5386; A61K45/00; A61P1/04; A61P3/10; A61P9/10; A61P11/06; A61P11/08; A61P13/10; A61P17/00; A61P19/02; A61P25/00; A61P25/08; A61P25/36; A61P27/16; A61P29/00; A61P31/04; A61P37/08; A61P43/00; C07D471/10; C07D498/10; C07D513/10
Domestic Patent References:
JP2005538959A
Foreign References:
WO2004092166A1
WO2004017965A1
WO2005013894A1
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita