レベチラセタムの徐放性製剤

Title:

レベチラセタムの徐放性製剤

Document Type and Number:

Japanese Patent JP5739080

Kind Code:

B2

Abstract:

The present invention relates to extended release pharmaceutical compositions of Levetiracetam and processes for preparing the same. The extended release tablet of Levetiracetam is with a core comprising of Levetiracetam and water dispersible rate controlling polymer, and the tablet core is optionally functional coated comprising a combination of water non-dispersible and/or water dispersible polymer. It provides extended therapeutically effective plasma levels over a twenty four hour period with diminished incidences of neuropsychiatric adverse events by eliminating the troughs and peaks of drug concentration in a patient's blood plasma. The composition also exhibits no food effect.

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Inventors:

Rajesh Ksirsagar
Mayank Joshi
Yogesh Raichandani

Application Number:

JP2007552811A

Publication Date:

June 24, 2015

Filing Date:

August 12, 2005

Export Citation:

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Assignee:

ALEMBIC LIMITED

International Classes:

A61K31/4015; A61K47/32; A61K47/34; A61K47/38; A61P25/08

Domestic Patent References:

JP200110951A
JP7138189A
JP2001131059A

Foreign References:

WO2004010998A1
WO2003101428A1
WO2001051033A1
WO2004000280A1

Attorney, Agent or Firm:

Kyousei Tamura
Samejima Mutsumi
Nagatoshi Shinagawa
Yasushi Morimoto

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