Title:
修飾型自己エピトープに対する抗腫瘍免疫応答
Document Type and Number:
Japanese Patent JP6490581
Kind Code:
B2
Abstract:
The present invention relates to the use of nucleic acids comprising sequences that encode tumour-associated epitopes in medicine and in particular in the treatment of cancer. The epitopes stimulate an immune reaction against the tumour and have a modification of deimination of arginine to citrulline.
Inventors:
Darland, Linda Gillian
Brentville, Victoria Anne
Rachel Lewis, Mezzerine Ham
Brentville, Victoria Anne
Rachel Lewis, Mezzerine Ham
Application Number:
JP2015525944A
Publication Date:
March 27, 2019
Filing Date:
August 07, 2013
Export Citation:
Assignee:
SCANCELL LIMITED
International Classes:
C12N15/12; A61K38/04; A61K39/00; A61K39/39; A61P35/00; C07K7/00
Domestic Patent References:
JP2009527498A | ||||
JP2007515924A | ||||
JP2010501475A | ||||
JP2006515268A | ||||
JP2006521093A | ||||
JP2006518982A | ||||
JP2002051785A |
Foreign References:
WO2010117694A1 |
Other References:
Proteomics,2012年,Vol.12,p.752-760
Attorney, Agent or Firm:
Kurata Masatoshi
Nobuhisa Nogawa
Naoki Kono
Tadashi Inoue
Ukai Ken
Shigeru Iino
Nobuhisa Nogawa
Naoki Kono
Tadashi Inoue
Ukai Ken
Shigeru Iino