Title:
大腸菌Ｂ２−ＳＴ１３１クローンの検査方法
Document Type and Number:
Japanese Patent JP6748987
Kind Code:
B2
Abstract:
The present invention pertains to a test method for identifying ESBL-producing Escherichia coli B2-ST131 clones, characterized by detecting a mutation of amino acid 34 to alanine in an amino acid sequence represented by SEQ ID NO: 1 among the amino acid sequences constituting part of the YahO protein. The present invention also pertains to a polynucleotide or antibody for detecting the mutation of amino acid 34 to alanine, a reagent composition containing either the polynucleotide or the antibody, and a reagent kit containing the reagent composition. Furthermore, the present invention pertains to a biomarker for identifying Escherichia coli B2-ST131 clones.
Inventors:
Seiji Kono
Akihiro Nakamura
Komatsu
Akihiro Nakamura
Komatsu
Application Number:
JP2017506605A
Publication Date:
September 02, 2020
Filing Date:
March 17, 2016
Export Citation:
Assignee:
National University Corporation Kobe University
International Classes:
C12Q1/04; C07K16/12; C12N15/09; C12N15/31; C12Q1/6844; C12Q1/6869; C12Q1/6872; G01N33/53; G01N33/569
Other References:
Escherichia coli strain RM2008 hypothetical protein (yahO) gene, complete cds. ,NCBI, GenBank,2010年 6月11日,GenBank:GU391860.1,p.1,http://www.ncbi.nlm.nih.gov/nuccore/289152316, 検索日:2016年6月3日
Anal. Chem., 2010年,Vol.82,p.2717-2725
JCM, 2014年,Vol.52, No.4,p.1034-1040
Anal. Chem., 2010年,Vol.82,p.2717-2725
JCM, 2014年,Vol.52, No.4,p.1034-1040
Attorney, Agent or Firm:
Takashi Shoji
Yuriko Shinobu
Takuya Osugi
Yuriko Shinobu
Takuya Osugi