Title:
抗インフルエンザウイルス剤、及び抗インフルエンザウイルス剤のスクリーニング方法
Document Type and Number:
Japanese Patent JP6778112
Kind Code:
B2
Abstract:
The present invention provides an anti-influenza virus agent that targets biomolecules of host cells including human cells and a method of screening a candidate molecule for the anti-influenza virus agent. That is, the present invention is an anti-influenza virus agent that has an effect of suppressing expression or a function of a gene that encodes a protein having an effect of suppressing incorporation of an influenza virus vRNA or an NP protein into influenza virus-like particles in host cells and the gene is at least one selected from the group including JAK1 gene and the like.
Inventors:
Yoshioka Kawaoka
Tokiko Watanabe
Kawakami Hideyoshi
Shinji Watanabe
Tokiko Watanabe
Kawakami Hideyoshi
Shinji Watanabe
Application Number:
JP2016550304A
Publication Date:
October 28, 2020
Filing Date:
September 18, 2015
Export Citation:
Assignee:
Japan Science and Technology Agency
International Classes:
A61K31/7105; A61K31/519; A61K31/713; A61P31/16; A61P43/00; C12Q1/26; C12Q1/6883
Foreign References:
| WO2011109217A1 |
Other References:
Blood,2012年,Vol.120, No.6,pp.1202-1209
Cell Host & Microbe,2014年12月10日,Vol.16,pp.795-805
BioDrugs,2013年10月,Vol.27, No.5,pp.431-438,添付資料はAuthor Manuscript
Arthritis Research & Therapy,2011年,Vol.13,Article Number R68, pp.1-15
Clinical Immunology,2003年,Vol.106,No.213-225
Cell Host & Microbe,2014年12月10日,Vol.16,pp.795-805
BioDrugs,2013年10月,Vol.27, No.5,pp.431-438,添付資料はAuthor Manuscript
Arthritis Research & Therapy,2011年,Vol.13,Article Number R68, pp.1-15
Clinical Immunology,2003年,Vol.106,No.213-225
Attorney, Agent or Firm:
Yasushi Matsunuma
Norihiko Ara
Nishizawa Kazumi
Makiko Otsuki
Masatake Shiga
Suzuki Mitsuyoshi
Norihiko Ara
Nishizawa Kazumi
Makiko Otsuki
Masatake Shiga
Suzuki Mitsuyoshi