Title:
ＳＡＰ枯渇剤としてのＤ−プロリン誘導体
Document Type and Number:
Japanese Patent JP6789288
Kind Code:
B2
Abstract:
The present invention relates to the compound ((2R,2′R)-bis(((tetrahydro-2H-pyran-4-carbonyl)oxy)methyl) 1,1′-adipoylbis(pyrrolidine-2-carboxylate), pharmaceutical compositions comprising the same and the use of the same for treatment of diseases or disorders wherein depletion of serum amyloid P component (SAP) would be beneficial, including amyloidosis, Alzheimer's disease, type 2 diabetes mellitus and osteoarthritis.
Inventors:
Alexi, Doni
Olivier, Mirgue
Jerome, Thum
Olivier, Mirgue
Jerome, Thum
Application Number:
JP2018521655A
Publication Date:
November 25, 2020
Filing Date:
October 25, 2016
Export Citation:
Assignee:
GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
International Classes:
C07D405/14; A61K31/4025; A61P3/10; A61P19/02; A61P25/28; A61P43/00
Domestic Patent References:
| JP2005515211A | ||||
| JP2007505890A | ||||
| JP11209343A |
Attorney, Agent or Firm:
Hiroyuki Nagai
Yukitaka Nakamura
Yasukazu Sato
Satoru Asakura
Hiroyuki Fujii
Hiroshi Sorimachi
Yukitaka Nakamura
Yasukazu Sato
Satoru Asakura
Hiroyuki Fujii
Hiroshi Sorimachi