Title:
ＰＳＰＬＡ１による甲状腺疾患の検出方法、情報提供方法及び試薬
Document Type and Number:
Japanese Patent JP6937607
Kind Code:
B2
Abstract:
PROBLEM TO BE SOLVED: To provide a method for detecting a thyroid disorder by measuring the concentration of phosphatidylserine specific phospholipase A1, a method for determining the effects of a treatment of a thyroid disorder, and a reagent.SOLUTION: There is provided a method of detecting a thyroid disorder by measuring phosphatidylserine specific phospholipase A1 of a human sample. There is also provided a method for providing information for determining the effects of a treatment of a patient with a thyroid disorder, the method associating measuring the phosphatidylserine specific phospholipase A1 in the sample derived from the patient, its measured value and the effects of the treatment.SELECTED DRAWING: Figure 1
Inventors:
Hiroshi Yatomi
Kurano Shin
Kazuki Nakawata
Koji Igarashi
Shimamoto Reishi
Kurano Shin
Kazuki Nakawata
Koji Igarashi
Shimamoto Reishi
Application Number:
JP2017092767A
Publication Date:
September 22, 2021
Filing Date:
May 09, 2017
Export Citation:
Assignee:
Tosoh Corporation
National University Corporation Tokyo University
National University Corporation Tokyo University
International Classes:
G01N33/68; C12Q1/44; G01N33/573
Domestic Patent References:
| JP2008203041A | ||||
| JP2012032278A |
Other References:
Junken Aoki,Structure and function of phosphatidylserine-specific phospholipase A1,Biochim Biophys Acta,2002年05月23日,Vol.1582 No.1-3,Page.26-32
藏野信,血中グリセロリゾリン脂質産生酵素はバセドウ病で上昇する,日本内科学会雑誌 ,2019年02月28日,Vol.108 臨時増刊号,Page.267
中渡一貴,バセドウ病におけるPS‐PLA1の新規バイオマーカーとしての有用性に関する検討,臨床病理,2018年10月15日,Vol.66 補冊,Page.129
Nakawatari Kazuki,Elevated phosphatidylserine-specific phospholipase A1 level in hyperthyroidism,Clinica chimica acta,2020年01月21日,Vol.503,Page.99-106
藏野信,血中グリセロリゾリン脂質産生酵素はバセドウ病で上昇する,日本内科学会雑誌 ,2019年02月28日,Vol.108 臨時増刊号,Page.267
中渡一貴,バセドウ病におけるPS‐PLA1の新規バイオマーカーとしての有用性に関する検討,臨床病理,2018年10月15日,Vol.66 補冊,Page.129
Nakawatari Kazuki,Elevated phosphatidylserine-specific phospholipase A1 level in hyperthyroidism,Clinica chimica acta,2020年01月21日,Vol.503,Page.99-106