Login| Sign Up| Help| Contact|

Patent Searching and Data


Document Type and Number:
Japanese Patent JPH0438754
Kind Code:
B2
Abstract:
Carbapenems having the formula:wherein:R1 is hydrogen or methyl;R4 and R5 are independently H, CH3-, CH3CH2-, (CH3)2CH-, HOCH2-, CH3CH(OH)-, (CH3)2C(OH)-, FCH2, F2CH-, F3C-, CH3CH(F)-, (CH3)2C(F)-, CH3CF2-;L is a bridging group comprising substituted or unsubstituted C1-C4 straight, C2-C6 branched or C3-C7 cycloalkyl groups wherein the substituents are selected from C1-C6 alkyl, O-C1-C6 alkyl, S-C1-C6 alkyl, CF3, N(C1-C6 alkyl)2;32 is mono- or bicyclic quaternary heteroaryl, andY is i) COOH or a pharmaceutically acceptable ester or salt thereof,ii) COOR wherein R is a removable carboxy protecting group,iii) COOM wherein M is an alkali metal, oriv) COO; provided that when Y is other than iv) a counterion Z is provided;their preparatrion and antibiotic use are disclosed.

More Like This:
JPS571080664-SUBSTITUTED-2-OXOAZETIDINE DERIVATIVE AND ITS PREPARATION
JP2002515882[Title of Invention] Carbapenem antibacterial compound, composition containing the compound, and therapeutic method.
Application Number:
JP27937985A
Publication Date:
June 25, 1992
Filing Date:
December 13, 1985
Export Citation:
Click for automatic bibliography generation   Help
International Classes:
C07D477/00; A61K31/397; A61K31/40; A61K31/44; A61K31/495; A61K31/53; A61P31/04; C07D477/14; C07F7/18; C07F9/6558



 
Next Patent: JPS438755