Document Type and Number:
Japanese Patent JPH0448779
Kind Code:
B2
Abstract:
N-acylated mercapto- alpha -amino acids of the general formula (I) are prepared by reacting a nitrile of the general formula R1-CN (II) at a temperature between 0 DEG C. and 100 DEG C. in water or in a mixture of water and an organic solvent which is at least partially miscible with water, in the presence of a base with a mercapto- alpha -amino acid of the general formula (III) and subsequently releasing the N-acylated mercapto- alpha -amino acid of general formula (I) with an acid. Mercapto- alpha -amino acids can be selectively acylated on the amino group in this manner in a relatively simple manner.
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Inventors:
HANSUUPEETAA KURIMAA
KAARUHAINTSU DORAUTSU
KAARUHAINTSU DORAUTSU
Application Number:
JP20396888A
Publication Date:
August 07, 1992
Filing Date:
August 18, 1988
Export Citation:
Assignee:
DEGUSSA
International Classes:
C07D333/24; C07B43/06; C07C51/08; C07C67/00; C07C313/00; C07C319/12; C07C323/51; C07C323/59; C07D213/80; C07D213/81; C07D213/82; C07D325/00; C07D333/22; C07D521/00; C07F9/02; C07F9/50
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