Document Type and Number:
Japanese Patent JPH0514714
Kind Code:
B2
Abstract:
A benzoxathiin derivative having the formula wherein R<1> represents hydrogen atom or a lower alkyl group, and R<2> represents a lower alkyl group or an aralkyl group, or a pharmaceutically acceptable acid addition salt thereof Pharmaceutical compositions containing these compounds are extremely excellent as to anti-arrhythmic effect, while toxicity and side-effects are very low as compared to the conventional compounds, so that they can be used safely in the medical field, preferably as an ideal remedy for disorders of the cardiovascular system such as arrhythmia, angina pectoris, hypertension and the like. Said benzoxathiin derivative can be produced economically and effectively by reacting an intermediate compound having the general formula with an amine having the formula R<1>R<2>NH, wherein R<1> and R<2> have the same meanings as defined above.
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Inventors:
HORI MIKIO
Application Number:
JP4473084A
Publication Date:
February 25, 1993
Filing Date:
March 08, 1984
Export Citation:
Assignee:
SUNTORY LTD
International Classes:
A61K31/39; A61P9/00; A61P9/06; A61P9/08; A61P9/10; A61P9/12; C07D327/06; C07D411/12
Next Patent: JPH0514715