Title:
【発明の名称】抗関節炎剤としてのビスホスホン酸誘導体
Document Type and Number:
Japanese Patent JPH06500112
Kind Code:
A
Abstract:
The bisphosphonates of formula (III) R2-X-(CW)m1-CR3R4-CH2-CM[PO-(OR1)2]2(III) bicyclic bisphosphonates (V), and cyclic bisphosphonates (VII) are useful as anti-arthritic agents and do not have the side effects of anti-arthritic agents which are prostaglandin synthetase inhibitors.
Inventors:
Nougent, Richard Allen
Application Number:
JP51508091A
Publication Date:
January 06, 1994
Filing Date:
August 09, 1991
Export Citation:
Assignee:
The Up John Company
International Classes:
A61K31/665; A61K31/67; A61K31/675; A61P29/00; A61P43/00; C07F9/38; C07F9/40; C07F9/58; C07F9/60; C07F9/6533; C07F9/6539; C07F9/6541; C07F9/655; A61K31/66; C07F9/6553; C07F9/6568; C07F9/6571; (IPC1-7): C07F9/40; A61K31/66; A61K31/665; A61K31/67; A61K31/675; C07F9/58; C07F9/60; C07F9/6533; C07F9/6539; C07F9/6541; C07F9/655; C07F9/6553; C07F9/6568
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)