Title:
【発明の名称】1H-インドール-1-官能性sPLA▲下2▼インヒビター
Document Type and Number:
Japanese Patent JPH10503208
Kind Code:
A
Abstract:
A class of novel 1H-indole-1-functional compounds is disclosed together with the use of such indole compounds for inhibiting sPLA2 mediated release of fatty acids for treatment of conditions such as septic shock. The compounds are 1H-indole-1-acetamides, 1H-indole-1-acetic acid hydrazides, and 1H-indole-1-glyoxylamides.
Inventors:
Burke, Nicholas Jay
Dillard, Robert Di
Doraheim, Susan Yee
Dillard, Robert Di
Doraheim, Susan Yee
Application Number:
JP50588596A
Publication Date:
March 24, 1998
Filing Date:
July 20, 1995
Export Citation:
Assignee:
ELI LILLY AND COMPANY
International Classes:
A61K31/405; A61K31/403; A61K31/404; A61P1/00; A61P11/00; A61P27/16; A61P29/00; A61P31/04; A61P37/08; A61P43/00; C07D209/08; (IPC1-7): C07D209/08; A61K31/405
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)