Title:
【発明の名称】ネイセリア(Neisseria)菌からのヘモグロビン受容体
Document Type and Number:
Japanese Patent JPH10508469
Kind Code:
A
Abstract:
The present invention relates to novel bacterial hemoglobin receptor proteins and genes that encode such proteins. The invention is directed toward the isolation, characterization, diagnostic and therapeutic use of bacterial hemoglobin receptor proteins, nucleic acid encoding such proteins, recombinant expression constructs comprising such nucleic acids and cells transformed therewith, and antibodies and epitopes of such hemoglobin receptor proteins. The invention relates particularly to hemoglobin receptor proteins and genes encoding such proteins from Neisseria species, especially N. meningitidis and serotypes thereof, and N. gonorrhoeae. Methods for the diagnostic and therapeutic use of the proteins, epitopes, antibodies and nucleic acids of the invention are also provided, including the use of the proteins, epitopes, antibodies and nucleic acids of the invention for the production of vaccines effectinve in providing immunization of a human against infection by pathogenic bacteria of Neisseria species.
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Inventors:
So, Magdalene
Fa, vivian
Heflon, Fred
Nassie, Xavier
Marc Henry Pauille
Fa, vivian
Heflon, Fred
Nassie, Xavier
Marc Henry Pauille
Application Number:
JP51348296A
Publication Date:
August 25, 1998
Filing Date:
October 17, 1995
Export Citation:
Assignee:
Oregon Health Sciences University
International Classes:
C12N15/09; A61K39/00; A61K39/095; A61K39/112; A61K39/395; A61P31/04; C07K14/22; C12N1/21; C12N5/00; C12N5/10; C12N15/00; C12N15/12; C12P21/02; C12P21/08; A61K38/00; C12R1/01; C12R1/19; C12R1/91; (IPC1-7): C12N15/09; A61K39/00; A61K39/095; A61K39/112; A61K39/395; C07K14/22; C12N5/10; C12P21/02; C12P21/08
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)