Title:
４，５−エポキシモルヒナン誘導体を含有する安定な固形製剤
Document Type and Number:
Japanese Patent JPWO2008133330
Kind Code:
A1
Abstract:
It is an object of the present invention to provide a stable solid preparation comprising a 4,5-epoxymorphinan derivative or a pharmacologically acceptable acid addition salt thereof as an effective ingredient. That is, the present invention provides the stable solid preparation comprising the 4,5-epoxymorphinan derivative or the pharmacologically acceptable acid addition salt thereof as the effective ingredient, and comprising sodium thiosulfate, a sugar or a sugar alcohol and hydroxypropylcellulose having a low degree of substitution in an amount of 1 to 30% by weight per weight of a unit containing the effective ingredient.
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Inventors:
Takagi Takashi
Koto Ota
Yasuhide Horiuchi
Masato Kobayashi
River Saki Junko
Horizawa Eijiro
Koto Ota
Yasuhide Horiuchi
Masato Kobayashi
River Saki Junko
Horizawa Eijiro
Application Number:
JP2009511919A
Publication Date:
July 29, 2010
Filing Date:
April 25, 2008
Export Citation:
Assignee:
TORAY INDUSTRIES,INC.
Maruho Co., Ltd.
Maruho Co., Ltd.
International Classes:
A61K31/485; A61K9/14; A61K9/16; A61K9/20; A61K9/28; A61K9/48; A61K47/02; A61K47/10; A61K47/26; A61K47/36; A61K47/38; A61P11/14; A61P17/04; A61P25/02
Attorney, Agent or Firm:
Hiroaki Sakai
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