2-オキソ-1-ピロリジン誘導体、それらの製造方法及びそれらの使用

Japanese Patent JP4121744

B2

The invention concerns 2-oxo-1-pyrrolidine derivatives of general formula (B. geometrical isomers, enantiomers, diastereoisomers, mixtures of each of these and pharmaceutically acceptable salts thereof. whereinR¹ is methyl,R² and R⁴ are hydrogen.R³ is alkyl or haloalkenyl, andX is -COOH. -COOMe or -COOEt.

WO/2002/042268	EP4 RECEPTOR SELECTIVE AGONISTS IN THE TREATMENT OF OSTEOPOROSIS
WO/2002/026750	PHOSPHINO-AMINOPHOSPHINES, CATALYST COMPLEXES AND ENANTIOSELECTIVE HYDROGENATION

Deferding, Edmond
Kenda, Benowa
Larman, Benedict
Mattagne, Alain
Michelle, Philip
Paso, patrick
Taraga, Patrice

JP2001561734A

July 23, 2008

February 21, 2001

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Yusebe Pharma Societe Anonym

C07D207/27; C07D401/04; A61K31/4015; A61K31/4025; A61K31/41; A61K31/4178; A61K31/4188; A61K31/4192; A61K31/4196; A61K31/422; A61K31/4245; A61K31/427; A61K31/433; A61K31/4439; A61K31/497; A61K31/506; A61K31/541; A61P9/00; A61P9/06; A61P9/10; A61P11/00; A61P11/06; A61P21/00; A61P25/00; A61P25/04; A61P25/06; A61P25/08; A61P25/14; A61P25/16; A61P25/20; A61P25/22; A61P25/24; A61P25/28; A61P25/30; A61P27/16; A61P37/08; C07B61/00; C07C237/06; C07C237/12; C07D207/26; C07D207/273; C07D207/277; C07D307/33; C07D401/06; C07D403/04; C07D403/06; C07D403/12; C07D405/04; C07D409/04; C07D413/04; C07D417/04; C07D495/04

JP62267226A
JP59167514A
JP7149639A
JP60252461A
JP2006022107A
JP2006022108A
JP2003528828A
JP2003515564A

WO1999013911A1
GB1309692B

Glozman, O. M. et al.,"Synthesis and anticonvulsive activity of 4-phenyl-2-pyrrolidinone-1-acetic acid amides"s,Khimiko-Farmatsevticheskii Zhurnal (1980), 14(11), 43-8,1980年,Vol.14, No.11,pp.43-48
Prous, J. et al.,"Levetiracetam",Drugs of the Future,1994年,Vol.19, No.2,pp.111-113

Hideto Asamura
Hajime Asamura
Naganuma Akio
Yukihiro Ikeda

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