Title:
9-置換ミノサイクリン化合物
Document Type and Number:
Japanese Patent JP4925549
Kind Code:
B2
Abstract:
The present invention pertains, at least in part, to novel 9- substituted minocycline compounds. These minocycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression.
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Inventors:
Nelson Mark El.
Fréchette Roger
Bisky peter
Ismail Mohamed
Bowser Todd
Dumoney Jimmy
Lenny Glen
Ryugui
Koza Darrell
Sherhan Paul
Stapleton Karen
Hawkins Paul
Batia beena
Barma Athur
McIntyre Laura
Warcoltad
Fréchette Roger
Bisky peter
Ismail Mohamed
Bowser Todd
Dumoney Jimmy
Lenny Glen
Ryugui
Koza Darrell
Sherhan Paul
Stapleton Karen
Hawkins Paul
Batia beena
Barma Athur
McIntyre Laura
Warcoltad
Application Number:
JP2002509074A
Publication Date:
April 25, 2012
Filing Date:
June 29, 2001
Export Citation:
Assignee:
TRUSTEES OF TUFTS COLLEGE
International Classes:
C07C237/26; C07D317/58; A61K31/65; A61P31/04; C07C237/00; C07C255/59; C07C271/22; C07C271/28; C07C271/30; C07C271/58; C07C275/30; C07C275/34; C07C275/38; C07C275/40; C07C275/42; C07C275/50; C07C275/54; C07C279/18; C07C311/06; C07C311/13; C07C311/21; C07C331/24; C07C333/08; C07C335/22; C07C381/10; C07D295/155; C07D317/62; C07F9/40; A61K; C07C
Domestic Patent References:
| JP2009029785A |
Foreign References:
| GB921252B |
Other References:
P.Sum et al.,J.Med.Chem.,1994年,vol.37,pp.184-188
P.Orth et al.,J.Mol.Biol.,1999年,vol.285,pp.455-461
P.Orth et al.,J.Mol.Biol.,1999年,vol.285,pp.455-461
Attorney, Agent or Firm:
Hatsushi Shimizu