Title:
PRODRUG OF 9-AMINOMETHYL TETRACYCLINE COMPOUND
Document Type and Number:
Japanese Patent JP2011153142
Kind Code:
A
Abstract:
To provide a prodrug of 9-aminomethyl substituted tetracycline compound and a method for using the compound, and to provide a pharmaceutical composition comprising the compound.
There is provided a compound or pharmaceutically acceptable salts thereof expressed by formula (IV), wherein Q" is -(C=O)-E3=G3; E3 is oxygen, nitrogen, or a covalent bond; and G3 is alkyl; heterocyclicalkyl; aryl; alkylcarbonyloxyalkyl; arylcarbonyloxyalkyl; alkyloxycarbonyloxyalkyl; arylalkylcarbonyloxyalkyl; alkyloxyalkylcarbonyloxyalkyl; or alkoxyalkoxycarbonyloxyalkyl.
Inventors:
KWASI OHEMENG
AMOO VICTOR
KIM OAK
BOWSER TODD
ASSEFA HAREGEWEIN
BHATIA BEENA
BERNIAC JOEL
CHEN JACKSON
GRIER MARK
HONEYMAN LAURA
PAN JINGWEN
MECHICHE RACHID
AMOO VICTOR
KIM OAK
BOWSER TODD
ASSEFA HAREGEWEIN
BHATIA BEENA
BERNIAC JOEL
CHEN JACKSON
GRIER MARK
HONEYMAN LAURA
PAN JINGWEN
MECHICHE RACHID
Application Number:
JP2011026689A
Publication Date:
August 11, 2011
Filing Date:
February 10, 2011
Export Citation:
Assignee:
PARATEK PHARM INNC
International Classes:
C07C271/22; A61K31/27; A61P31/04; A61P31/12; A61P33/00; C07C237/26; C07C271/54; C07C275/28; C07C275/30; C07D211/18
Attorney, Agent or Firm:
Hatsushi Shimizu
Koichi Niimi
Koichi Niimi
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