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Patent Searching and Data


Title:
ADSORBENT FOR IgG PURIFICATION AND METHOD FOR PURIFYING IgG
Document Type and Number:
Japanese Patent JP2004189658
Kind Code:
A
Abstract:

To provide an adsorbent for IgG purification utilizing a novel peptide or protein having bindability to the Fc fragment of IgG and to provide a method for purifying IgG.

The Fc fragment of IgG of an animal origin is used as a target substance. The amino acid sequence of a peptide having bindability to the target substance is identified by screening by a pharge display method. A peptide obtained in this way and having an amino acid sequence represented by sequence numbers 1 to 164 or having an amino acid sequence obtained by subjecting to modification or the substitution, insertion, and/or elimination of amino acid residues within the scope not detrimental to the bindability to the Fc fragment of IgG in the amino acid sequence is immobilized on a carrier as an affinity ligand, and IgG is purified by using it.


Inventors:
SUZUKI MASATSUGU
TSUNODA HIROYUKI
KOBAYASHI TOMOMI
MATSUMOTO MEGUMI
Application Number:
JP2002358615A
Publication Date:
July 08, 2004
Filing Date:
December 10, 2002
Export Citation:
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Assignee:
PEPTIDE DOOR CO LTD
International Classes:
B01J20/26; B01J20/281; C07K1/22; C07K7/06; C07K7/08; C07K16/00; (IPC1-7): C07K7/06; B01J20/26; C07K1/22; C07K7/08; C07K16/00
Attorney, Agent or Firm:
Shigeru Matsui